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The art of living healthy, guided by science and medicine.

TRAIN is built on years of academic research and clinical experience. Our founders lead the TARGet research group — an international initiative advancing cardiovascular and preventive health through translational science.

Science and medicine
About us

Bridging advanced medical research and everyday health.

Dr Nimrat Grewal and Dr Simran Grewal founded TRAIN Health Awareness to translate clinical insight into practical, daily habits. We empower individuals with the knowledge and tools to take control of their health and prevent non-communicable diseases.

Mission

Bridge the gap between science and habits.

To bridge the gap between advanced medical research and everyday health practices. We provide comprehensive information on risk factors, ongoing research projects, and the latest scientific findings to support a healthier lifestyle.

Vision

A world of informed, proactive individuals.

A world where individuals are well-informed about their health risks and proactive in managing them, supported by a community of engaged people who can make better health decisions backed by the latest research and technology.

Approach

Cutting-edge research, practical health advice.

We integrate clinical and scientific insight with everyday application — through the TRAIN Health app and our website, covering cardiovascular and musculoskeletal health, risk-factor management, and ongoing research studies.

TARGet Research Group

Advancing knowledge in cardiovascular & preventive health.

An internationally active academic research initiative led by clinician-scientists — bringing together surgeons, physicians, data scientists, and researchers across disciplines to translate science into clinical and societal impact.

Our work spans genetic and molecular research, real-world data collection, and lifestyle-based prevention — bridging the gap between science and everyday health.

20+
PhDs
driving translational and clinical research
5+
Postdocs
advancing genetic, clinical, and data-driven insights
100+
Publications
contributing to international research and innovation
50+
Collaborations
with leading academic and clinical institutions worldwide
Prof. Dr. Nimrat Grewal
Our Collaborators
Universitas Budapestinensis
Ghent University
Val d'Hebron
The Aortic Dissection Charitable Trust
Erasmus MC
Goteborgs Universitet
Yale University School of Medicine
Stichting Aortadissectie Nederland
NWO
Medizinische Universität
Hartstichting
Veritas Lux Mea
SIMS Hospital
Max Healthcare
University of Oxford
Monash University
Universite Paris Cite
Universität Hamburg
Region Hovedstaden
Uniklinik Koln
Medisch Centrum Jan Van Goyen
Mayo Clinic
NHS Guy's and St Thomas'
Universidad de Navarra
Amsterdam UMC
OLVG
Karolinska Institutet
Ospedali Dei Colli
CHU de Liege
Kings College London
Radboudumc
Scientific output

Selected publications from the TARGet group.

100+ peer-reviewed contributions across cardiovascular and preventive health. A representative selection. Full list available on request.

Machine Learning-driven Probability Calculators Can Accurately Predict 1-year Mortality After Proximal Humerus Fractures in Patients Over the Age of 65 Years

Machine Learning-driven Probability Calculators Can Accurately Predict 1-year Mortality After Proximal Humerus Fractures in Patients Over the Age of 65 Years

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Comparison of microstructural alterations in the proximal aorta between aortic stenosis and regurgitation

Comparison of microstructural alterations in the proximal aorta between aortic stenosis and regurgitation

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Spillage of bacterial products during colon surgery increases the risk of liver metastases development in a rat colon carcinoma model

Spillage of bacterial products during colon surgery increases the risk of liver metastases development in a rat colon carcinoma model

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The Prevalence of Coronary Artery Disease in Bicuspid Aortic Valve Patients: An Overview of the Literature

The Prevalence of Coronary Artery Disease in Bicuspid Aortic Valve Patients: An Overview of the Literature

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Sex Differences in the Histopathology of Acute Type A Aortic Dissections

Sex Differences in the Histopathology of Acute Type A Aortic Dissections

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Appraisal of ChatGPT's responses to common patient questions regarding acromioclavicular joint dislocations

Appraisal of ChatGPT's responses to common patient questions regarding acromioclavicular joint dislocations

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APECx-Anaesthesia, Perfusion and Surgical Practices in Cardiac Surgery: Main Study Protocol of a Modular Multiphase Prospective International Multicentre Observational Study

APECx-Anaesthesia, Perfusion and Surgical Practices in Cardiac Surgery: Main Study Protocol of a Modular Multiphase Prospective International Multicentre Observational Study

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Geranylgeranylacetone as Prevention for Postoperative Atrial Fibrillation (GENIALITY)

Geranylgeranylacetone as Prevention for Postoperative Atrial Fibrillation (GENIALITY)

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Corrective osteotomy in symptomatic clavicular malunion using computer- assisted 3-D planning and patient-specific surgical guides

Corrective osteotomy in symptomatic clavicular malunion using computer- assisted 3-D planning and patient-specific surgical guides

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Aortic root replacement for bicuspid aortic valve dysfunction does not impair survival rates

Aortic root replacement for bicuspid aortic valve dysfunction does not impair survival rates

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Surgery for Colorectal Cancer: A Trigger for Liver Metastases Development? New Insights into the Underlying Mechanisms

Surgery for Colorectal Cancer: A Trigger for Liver Metastases Development? New Insights into the Underlying Mechanisms

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Wall Shear Stress Directional Abnormalities in BAV Aortas: Toward a New Hemodynamic Predictor of Aortopathy?

Wall Shear Stress Directional Abnormalities in BAV Aortas: Toward a New Hemodynamic Predictor of Aortopathy?

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The role of hemodynamics in bicuspid aortopathy: a histopathologic study

The role of hemodynamics in bicuspid aortopathy: a histopathologic study

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Ventricular Septation and Outflow Tract Development in Crocodilians Result in Two Aortas with Bicuspid Semilunar Valves

Ventricular Septation and Outflow Tract Development in Crocodilians Result in Two Aortas with Bicuspid Semilunar Valves

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Practical Considerations of Remote Care in Thoracic Aortopathy in India

Practical Considerations of Remote Care in Thoracic Aortopathy in India

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Macrophages mediate colon carcinoma cell adhesion in the rat liver after exposure to lipopolysaccharide

Macrophages mediate colon carcinoma cell adhesion in the rat liver after exposure to lipopolysaccharide

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Intrinsic histological and morphological abnormalities of the pediatric thoracic aorta in bicuspid aortic valve patients are predictive for future aortopathy

Intrinsic histological and morphological abnormalities of the pediatric thoracic aorta in bicuspid aortic valve patients are predictive for future aortopathy

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Nationwide survey of Indian cardiac surgeons on the management of acute type A aortic dissection

Nationwide survey of Indian cardiac surgeons on the management of acute type A aortic dissection

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Disturbed remodeling and delayed fracture healing in pediatric pycnodysostosis patients

Disturbed remodeling and delayed fracture healing in pediatric pycnodysostosis patients

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A rare co-presentation of bicuspid aortic valve aortopathy and PTEN mutation: hypothesis- generating, not practice- changing

A rare co-presentation of bicuspid aortic valve aortopathy and PTEN mutation: hypothesis- generating, not practice- changing

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Are Thoracic Aortic Aneurysm Patients at Increased Risk for Cardiovascular Diseases?

Are Thoracic Aortic Aneurysm Patients at Increased Risk for Cardiovascular Diseases?

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Reply to the editor

Reply to the editor

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The Development of the Ascending Aortic Wall in Tricuspid and Bicuspid Aortic Valve: A Process from Maturation to Degeneration

The Development of the Ascending Aortic Wall in Tricuspid and Bicuspid Aortic Valve: A Process from Maturation to Degeneration

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Progerin Expression during Normal Closure of the Human Ductus Arteriosus: A Case of Premature Ageing?

Progerin Expression during Normal Closure of the Human Ductus Arteriosus: A Case of Premature Ageing?

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Treatment of a Recalcitrant Non-union of the Clavicle

Treatment of a Recalcitrant Non-union of the Clavicle

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Diversity and Representation in Cardiovascular Research: Evidence Gaps, Emerging Models, and Policy Implications

Diversity and Representation in Cardiovascular Research: Evidence Gaps, Emerging Models, and Policy Implications

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Comparison of cardiovascular risk profiles of patients with type A aortic dissection and thoracic aortic aneurysm: a retrospective multicentre study

Comparison of cardiovascular risk profiles of patients with type A aortic dissection and thoracic aortic aneurysm: a retrospective multicentre study

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Comparative evaluation of coronary disease burden: bicuspid valve disease is not atheroprotective

Comparative evaluation of coronary disease burden: bicuspid valve disease is not atheroprotective

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Bicuspid aortic valve: phosphorylation of c-Kit and downstream targets are prognostic for future aortopathy

Bicuspid aortic valve: phosphorylation of c-Kit and downstream targets are prognostic for future aortopathy

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Surgery-induced reactive oxygen species enhance colon carcinoma cell binding by disrupting the liver endothelial cell lining

Surgery-induced reactive oxygen species enhance colon carcinoma cell binding by disrupting the liver endothelial cell lining

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Can general histopathology distinguish bicuspid aortopathy?

Can general histopathology distinguish bicuspid aortopathy?

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Structural abnormalities in the non-dilated ascending aortic wall of bicuspid aortic valve patients

Structural abnormalities in the non-dilated ascending aortic wall of bicuspid aortic valve patients

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Brief Review: Racial Disparities in the Presentation and Outcomes of Patients with Thoracic Aortic Aneurysms

Brief Review: Racial Disparities in the Presentation and Outcomes of Patients with Thoracic Aortic Aneurysms

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The senescence of vascular smooth muscle cells in BAV-associated aortopathy

The senescence of vascular smooth muscle cells in BAV-associated aortopathy

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Beyond Survival: Assessing Quality of Life, Activity Level, and Ethnic Diversity in Aortic Dissection Survivors

Beyond Survival: Assessing Quality of Life, Activity Level, and Ethnic Diversity in Aortic Dissection Survivors

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Establishing reference values for aortic dimensions in the general Indian population and implications for global standards

Establishing reference values for aortic dimensions in the general Indian population and implications for global standards

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Letter to the editor: The motivators and barriers to a career in cardiothoracic surgery: a cross-sectional study among surgical residents in India

Letter to the editor: The motivators and barriers to a career in cardiothoracic surgery: a cross-sectional study among surgical residents in India

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Oral Antibiotic Prophylaxis Reduces Surgical Site Infection and Anastomotic Leakage in Patients Undergoing Colorectal Cancer Surgery

Oral Antibiotic Prophylaxis Reduces Surgical Site Infection and Anastomotic Leakage in Patients Undergoing Colorectal Cancer Surgery

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Can transforming growth factor beta and downstream signalers distinguish bicuspid aortic valve patients susceptible for future aortic complications?

Can transforming growth factor beta and downstream signalers distinguish bicuspid aortic valve patients susceptible for future aortic complications?

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Thoracic aortopathy in Marfan syndrome overlaps with mechanisms seen in bicuspid aortic valve disease

Thoracic aortopathy in Marfan syndrome overlaps with mechanisms seen in bicuspid aortic valve disease

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Allograft vs. autograft for chronic acromioclavicular joint instability: a systematic review and meta-analysis of outcomes and complications

Allograft vs. autograft for chronic acromioclavicular joint instability: a systematic review and meta-analysis of outcomes and complications

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The TRAIN Health Awareness Clinical Trial: Baseline Findings and Cardiovascular Risk Management in Aortic Dissection Patients

The TRAIN Health Awareness Clinical Trial: Baseline Findings and Cardiovascular Risk Management in Aortic Dissection Patients

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Beyond the tear: the enduring role of aortic pathology in the era of genomic medicine

Beyond the tear: the enduring role of aortic pathology in the era of genomic medicine

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Effect of Bicuspid or Tricuspid Aortic Valve on Preoperative Coagulation in Patients Scheduled for Thoracic Aortic Surgery

Effect of Bicuspid or Tricuspid Aortic Valve on Preoperative Coagulation in Patients Scheduled for Thoracic Aortic Surgery

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Extent of Coronary Artery Disease in Patients With Stenotic Bicuspid Versus Tricuspid Aortic Valves

Extent of Coronary Artery Disease in Patients With Stenotic Bicuspid Versus Tricuspid Aortic Valves

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The role of transforming growth factor beta in bicuspid aortic valve aortopathy

The role of transforming growth factor beta in bicuspid aortic valve aortopathy

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A Systematic Histopathologic Evaluation of Type-A Aortic Dissections Implies a Uniform Multiple-Hit Causation

A Systematic Histopathologic Evaluation of Type-A Aortic Dissections Implies a Uniform Multiple-Hit Causation

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Thoracic aortic atherosclerosis in patients with a bicuspid aortic valve; a case-control study

Thoracic aortic atherosclerosis in patients with a bicuspid aortic valve; a case-control study

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Aortic wall lamellar structure in phylogeny and in humans: insights from bicuspid and tricuspid aortic valve morphology

Aortic wall lamellar structure in phylogeny and in humans: insights from bicuspid and tricuspid aortic valve morphology

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Histopathology of aortic complications in bicuspid aortic valve versus Marfan syndrome: relevance for therapy?

Histopathology of aortic complications in bicuspid aortic valve versus Marfan syndrome: relevance for therapy?

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Human IgG3 with extended half-life does not improve Fc-gamma receptor- mediated cancer antibody therapies in mice

Human IgG3 with extended half-life does not improve Fc-gamma receptor- mediated cancer antibody therapies in mice

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Accuracy of point-of-care coagulation testing during cardiopulmonary bypass in a patient post COVID-19 infection

Accuracy of point-of-care coagulation testing during cardiopulmonary bypass in a patient post COVID-19 infection

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Acute aortic syndromes in India: The need for a nationwide program to increase awareness

Acute aortic syndromes in India: The need for a nationwide program to increase awareness

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Mendelian Randomization Suggests a Causal Link Between Glycemic Traits and Thoracic Aortic Structures and Diseases

Mendelian Randomization Suggests a Causal Link Between Glycemic Traits and Thoracic Aortic Structures and Diseases

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Adventitial adaptive immune cells are associated with ascending aortic dilatation in patients with a bicuspid aortic valve

Adventitial adaptive immune cells are associated with ascending aortic dilatation in patients with a bicuspid aortic valve

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Are acute type A aortic dissections atherosclerotic?

Are acute type A aortic dissections atherosclerotic?

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Exploring ethnic differences in the perioperative course of thoracic aortopathy

Exploring ethnic differences in the perioperative course of thoracic aortopathy

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Normal and abnormal development of the aortic valve and ascending aortic wall: a comprehensive overview of the embryology and pathology of the bicuspid aortic valve

Normal and abnormal development of the aortic valve and ascending aortic wall: a comprehensive overview of the embryology and pathology of the bicuspid aortic valve

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Is the intimal thickness a key contributor to thoracic aortopathy?

Is the intimal thickness a key contributor to thoracic aortopathy?

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Pathogenesis of aortic wall complications in Marfan syndrome

Pathogenesis of aortic wall complications in Marfan syndrome

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Risk for acquired coronary artery disease in genetic vs. congenital thoracic aortopathy

Risk for acquired coronary artery disease in genetic vs. congenital thoracic aortopathy

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Commentary: Transforming growth factor serum concentrations in patients with proven non- syndromic aortopathy

Commentary: Transforming growth factor serum concentrations in patients with proven non- syndromic aortopathy

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Bridging Barriers: Engaging Ethnic Minorities in Cardiovascular Research

Bridging Barriers: Engaging Ethnic Minorities in Cardiovascular Research

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Evidence Accumulates: Patients with Ascending Aneurysms Are Strongly Protected from Atherosclerotic Disease

Evidence Accumulates: Patients with Ascending Aneurysms Are Strongly Protected from Atherosclerotic Disease

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Ascending aorta dilation in association with bicuspid aortic valve: a maturation defect of the aortic wall

Ascending aorta dilation in association with bicuspid aortic valve: a maturation defect of the aortic wall

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The science is here. The evidence is building.

TRAIN is a clinician-led group working at the intersection of cardiovascular science, lifestyle medicine, and digital health. If your work intersects with ours, we'd like to collaborate.