GEN-TAAD: Aortic Patient Study - TRAIN Health Awareness

GEN-TAAD: Aortik Hasta Çalışması

Overview

The TARGet (Thoracic Aortic Research and Genetic Study) project is a comprehensive research initiative aimed at understanding the genetic and clinical factors contributing to thoracic aortic diseases. This project focuses on patients with aortic pathologies, including thoracic aortic aneurysms (TAA) and acute type A aortic dissections (ATAAD).

Objectives

Risk Stratification

To develop personalized risk stratification models that integrate genetic, clinical, and lifestyle factors to predict the likelihood of disease progression and complications.

Improve Patient Outcomes

To enhance the early detection and treatment of thoracic aortic diseases, ultimately improving patient outcomes and reducing mortality rates.

Methodology

The TARGet project involves the collection of extensive data from aortic patients, including:

Biobank Samples: Over 1000 aortic tissue samples and live aortic cells have been collected to support genetic and molecular analyses.

Clinical Data: Detailed patient histories, imaging studies, and clinical outcomes are recorded to identify correlations between genetic markers and disease characteristics.

Collaborative Efforts: The project collaborates with international research partners to ensure a diverse and comprehensive dataset, providing insights into societal, racial, and ethnic differences in aortopathy pathophysiology.

Progress and Findings

To date, the TARGet project has achieved significant milestones, including:

Development of Risk Models: Creation of preliminary models for personalized risk assessment, integrating genetic and clinical data.

Publications and Presentations: Numerous publications in high-impact scientific journals and presentations at international conferences, sharing our findings with the global medical community.

Future Directions

The TARGet project continues to expand its research efforts with the following goals:

Validation of Risk Models

Further refine and validate risk stratification models to ensure accuracy and reliability.

Clinical Trials

Initiate clinical trials to test the effectiveness of new diagnostic and therapeutic approaches based on our research findings.

Patient Education and Engagement

Develop educational resources and tools to inform patients about their condition and involve them in their own healthcare decisions.

Train Programs

Interested in learning more?

If you’re interested in the GEN-TAAD study, contact us and our research team will follow up with you.

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